Extending the human lifespan is a multibillion-pound industry and has been hailed as the most fascinating scientific challenge in modern history. But if a drug to achieve longevity is ever discovered, one thing looks certain: it is highly unlikely to work on women – and almost inconceivable that it will work on mothers.

That is because, say experts, cages in laboratories across the world are filled with white mice who share a striking similarity: they are all male.

This is a serious problem, said Dr Steven Austad, a biologist and the author of the bestselling Methuselah’s Zoo, because the sex differences between rodents are significant – and the differences between virgin female mice and mice that have given birth are even larger.

About 75% of the drugs that extend lifespan in mice work only on males: the drugs were developed on male mice then belatedly tested on both sexes, only to discover the females did not respond.

  • frankgrimeszz@lemmy.world
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    4 months ago

    Interestingly, there were no cries of “sex bias” when only men were subjected to the experimental drug pyridostigmine bromide during the Gulf War, which permanently damaged their health. I wonder how it would affect women.

    • bassomitron@lemmy.world
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      4 months ago

      While true, women dodged a bullet there, you’re missing the bigger picture and entire point of the article: Women as a whole are losing out on potentially life-saving treatment to a much larger degree than some very specific fringe case from over 30 years ago.

    • Flying Squid@lemmy.worldM
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      4 months ago

      There are also no cries of sex bias with the Tuskeegee syphillis experiment. Do you know what that might be? Do you think that maybe sexism isn’t the issue when it comes to experimenting on humans?

    • Shawdow194@kbin.run
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      4 months ago

      Yeah but we cant change history. We can progress in the future with less bias towards a particular group, and broader encompassing studies