The water doesn’t make a difference. What’s killing the bacteria is the heat. The water just changes the method of heat transfer. But as others have already said, killing the bacteria may not necessarily make it safe

What do you mean? People watch twitch, why would this be any different?

The pancreas is not really stable enough to be implanted in at all. Other organs you’re imagining like liver, stomach, heart, etc. have a solid lining that can be cut open and stitched back together. The pancreas is more like a cluster of loose cells with veins throughout and held together by a very thin, tissue paper lining. If you try to open it and insert cells, you’re not going to be able to put it back together.

That’s why cells are usually put in the liver, which has a large vein going directly to the pancreas. Close proximity and high blood supply. Implanting in the pancreas will likely never be an option unless you can drastically reduce the volume of cells.

Our lab was working on implanting the stem cells on a porous scaffold in the fat pad of the stomach as an alternative

Unfortunately, that doesn’t necessarily negate the requirement for immunosuppresors or some other kind of immuno protection. If it is Type 1 diabetes, the person originally became diabetic because the immune system saw certain markers on the beta cells (insulin producing cells) as a threat. So, if you recreate the beta cells, there is still a possibility that it will happen again. You are fighting your own immune system. Someone in our lab was studying encapsulation of cells to create a protective barrier around them for this very issue

If the person was Type 2, this might be less of a risk since type 2 can also be due to high insulin resistivity. There are a lot of other factors involved, though, it’s not straightforward

I literally worked in a research lab working on islet cell therapies for diabetes in the US. This has actually been done many times before with cells from cadavers. It has been successful, although most the of the time the person reverts back after a few years because installing in the hep

The issues we were trying to solve in the lab were

1. Finding a good place to transplant where the cells will last: Implanting in the hepatic region (liver), which is the most common place to implant, is toxic to the cells over time hence only lasting 3-5 years. The cells need a really good blood supply and the volume you’re transplanting can’t be easily transplantes in the pancreas or kidney capsules (where many successful studies were performed in mice and rats)

2. Being able to consistently make a high volume of stem cells that are fully grown into insulin producing cells: Cadaver cells usually require 3-5 donors for 1 person and require the receiver to be on lifelong immunosuppresors due to the immune response. Depending on the kind of stem cells, the patient may still even need immunosuppresors due to the cell type you’re converting from

All this the say - the article says nothing about where the cells where transplanted, where they came from, or whether the person has Type 1 or Type 2 diabetes. Although it is still a feat, it is likely not the first time it has been done, and we’re still a long ways off from a cure

Dr. Death was about gross negligence in medicine and the failure of the medical system to prevent unqualified doctors from making it through the system. There’s no evidence that this study has anything to do with that

This title really overly praises him for 1) not doing much at all and 2) making changes that should have been made months ago

It’s really inspiring to see such a wide range of hobbies in this thread

The bad part is that their healthcare system still has to deal with the rising number of cases, but it’s not like there has been an unexpected spike from anything unusual

For those who dont feel like reading the whole article, here’s why:

“Much of the increase in kidney failure is caused by an ageing population. When age is taken into account, the number of people with kidney failure as a proportion of the population has remained fairly stable over the past decade, according to data from the registry.”

New fear unlocked

My experience may be too anecdotal to take into account, so I understand not caring about my specific experience. But I do think it’s a good idea to take life span into account, and from a quick google search the average lifespan of a Macbook air is generally 5-7 years (so really not far off).

Just something to consider that since parts aren’t replaceable, OP would have to pay the full amount of a new laptop at that time

I am not very familiar with framework but I did switch from macbooks to a dell gaming laptop years ago and I am so glad I did.

The macs are ridiculously expensive, and even if you break just the charger it costs a lot to replace. My laptop now I was able to get for nearly half the price and it runs games and programs that I used in college better than the mac ever could.

Every mac I ever owned completely died in 4-6 years of purchase. They’re basically guaranteed to not last a long time. My guess is you’re better off with getting a framework

I skin the potatoes and use a ricer. They are very smooth and creamy, not lumpy. I actually like boxed potatoes and fresh still taste 10x better

If you’re going to get one, highly recommend getting 240V instead of 110v/plug and play type. 240V are the only ones that can really keep up with the heat and give you that real jet feel in the tub.

If possible, keep it somewhere covered. We have it in our covered patio, which allows us to get use of it in any kind of weather and prevents mosquitos/other bugs coming around.

Chemical balancing can be pretty tough, we mostly keep a steady supply of bleach around to make sure it’s staying clean. One issue we had was the test strips never seemed to say the water was hard enough so we kept adding calcium hardner, but it ended up precipitating and making a rough coating on the seats (eventually we were able to clean it off). Ended up deciding it wasn’t a big deal if some values are out of range on the test strips as long as the stuff to keep people safe is balanced (ie chlorine)

If homemade mash tastes exactly like the box to you, you’re doing something wrong when you make them. I’m not saying instant is bad to have in a pinch, but having the dehydrated potatos in flakes immediately makes them starchier and have a more gluey consistency. Plus, there are tons of additives that definitely make it taste different from freshly cooked potatoes.

I disagree on this one, corn tortillas are really simple if you have a press. The dough is literally just mix masa and water. And to cook them, you just put it on a hot surface for 30 seconds. Meanwhile corn tortillas from the store are always so dry and tasteless, they’re rarely worth buying

A24 is truly a diamond in the rough, everything they make is so unique

It’s definitely a drop in quality. Just look at what is out in movie theaters these days. 90% of the movies are either sequels, marvel movies, or live action remakes of films that were already made. The amount of original storytelling or unique content has dropped rapidly in the past 5 years. As someone who grew up loving going to the movie theater, it makes me so sad, and I rarely go anymore.

Whether you like or hate Barbie or Oppenheimer, they were pretty much some of the only completely brand new high production value movies that came out in the last year, which I believe is part of why they were so popular. People are craving originality, even if a lot of them don’t realize it

A yearly review is generally more for them to give you feedback so you really don’t have to ask questions if you don’t want to. If you’ve been doing a decent job you have nothing to be anxious about. But here are some questions you could consider asking: What do you consider my strengths? Is there anything I can improve on? I would like to develop my skills in xyz, are there any opportunities in the company for me to do that? Or do you have recommendations for how I could do that outside of the company? What are the career path options after level tech 2? Am I meeting your expectations for where I should be at the current point in my career? What direction do you see the company/our team moving in in the next few years? How could I help us align with that?