Thank you for your very comprehensive response. I am currently trying to replace the outer silicone gaskets with cork, with mixed results, which is why I hoped that natural rubber may do the trick. I also did see that the inner O-rings were made of EPDM, so I hoped that those could be replaced with something better for the environment.
I actually wasn’t aware of the natural rubber vulnerability to e-coli… And the spigot will be placed in a highly humid environment. So I guess back to the drawing board.